BIOFLEX Science


Compared to traditional treatment, patients recover from musculoskeletal and peripheral nerve injuries with less scar tissue, accelerated cell regeneration, and improved function through photobiomodulation process.

Photobiomodulation

The science behind the healing
Photobiomodulation (PBM), also known as Laser Therapy, operates on a fascinating principle that harnesses the power of light to stimulate healing and rejuvenation within the body. Imagine your cells as tiny powerhouses, each with specific tasks to keep your body functioning optimally. Over time, these cells encounter stress, injury, or overuse causing them to deteriorate. This is where PBM steps in. Using Laser Therapy, gentle pulses of light are delivered to target the affected areas of the body. These photons are absorbed on a cellular level by mitochondria—”the powerhouse of the cell”—where the Cytochrome C Oxidase enzyme is activated, releasing nitric oxide and oxygen molecules. This release effectively counters oxidative stress, restarts ATP production, energizes cells, and initiates a cascade of physiological reactions, leading to the restoration of normal cell structure and function.
Additionally, the release of nitric oxide and oxygen triggers the production of the NF-kB protein, a cellular protector, while activating the calcium pump, restoring cellular regulation. As oxygen floods the bloodstream, vessels and capillaries form, setting off a series of healing effects. Inflammation, whether induced by infection or trauma, is quickly reduced, allowing systemic tissue repair to unfold seamlessly throughout the body. This comprehensive approach to healing, promotes wellness and vitality from within. Whether you’re looking to address an injury, manage pain, or enhance overall well-being, PBM offers a non-invasive, drug-free solution that taps into your body’s natural healing abilities.
Photobiomodulation starts the healing process at the mitochondria
  • Photomechanical response activates the calcium pump to start the tissue healing process
  • Cellular protective protein is released (NF-kB, also known as Nuclear Factor Kappa Beta) that defends against cell stress
  • The increase in oxygen starts the vasodialation promotes blood flow and the formation of new capiliaries

What is Laser Therapy?

Laser Therapy is known by many terms, including cold or low-level laser therapy (LLLT). Recently, experts have chosen photobiomodulation therapy (PBMT) as a more accurate term that describes the therapeutic use of red and near-infrared wavelengths of light energy from laser OR light emitting diodes (LEDs) that interact with photoreceptors to produce photochemical reactions that have a positive effect on cellular metabolism and recovery from damage and inflammation.

BIOFLEX® is the only laser therapy company that utilizes powerful Class 3b lasers together with large surface arrays of bicolour LEDs that affect a large volume of circulating blood as well as underlying tissues resulting in both a powerful systemic and direct photobiomodulation effect. The overall clinical effect of targeting both the injured/diseased tissues as well as the surrounding circulatory system is an unsurpassed accelerated healing response and decrease in pain, inflammation, edema and associated symptoms.

Clinical Effects of Laser Therapy

BIOFLEX Laser Therapeutic Platforms

The therapeutic effects of Laser Therapy at the cellular level have proven to increase ATP levels and DNA synthesis and are specific to enhance mitochondrial membrane potential and function. The light emitted using the various laser therapy systems stimulate the photochemical reactions within the cells supporting mitochondrial activities. This can create beneficial changes in cell behavior and accelerate the natural healing process. Mitochondria contain photoreceptors that absorb the photons from light and convert these into ATP – energy that can be utilized to stimulate cellular activities and biological processes. Proper mitochondrial function and ATP production are critical to the process of neuro-protection modulation, regeneration, cognitive enhancement, and the prevention and alleviation of a number of other neurological pathologies. Laser Therapy is effective in:

Musculoskeletal Injuries

The most common applications are muscle strains, ligament sprains, tendinopathies, cartilage tears bursitis and other injuries to the musculoskeletal system. Whether it’s a sports injury, overuse condition, or an accident, the goal of treatment is to accelerate the healing process and decrease symptoms which allows the clinician to initiate manual and exercise therapies much sooner.

Wound Healing

BIOFLEX Laser Therapy has been proven to accelerate surgical wound healing, dermal ulcers, diabetic lesions and all other recalcitrant wounds. This results in increased angiogenesis, neovascularization, collagen secretion and decreased inflammatory exudate and provides epithelization of the wound, improved arterial perfusion and, regeneration of the local and regional tissues. (Professional Systems)

Arthritis

Chronic progressive forms of joint degeneration can be effectively managed with BIOFLEX Laser Therapy. All of the arthritides from early to late stages will respond to treatment resulting in decreased pain, inflammation, stiffness and edema. Research has even shown repair and regeneration of eroded hyaline cartilage when exposed to Laser Therapy. (Professional Systems)

Nerve Healing

From diabetic neuropathy to discogenic radiculopathy to carpal tunnel syndrome, BIOFLEX Laser Therapy can accelerate nerve healing and decrease paraesthesia and nerve pain as a result of direct absorption of light. Many peer reviewed clinical trials and lab studies have proven Laser Therapy is an effective therapy for nerve healing and has no known side effects.

Light Spectrum in Laser Therapy

The effectiveness of wavelengths of light with respect to photobiomodulation therapy can be characterized by the action spectra of the target photoacceptors (e.g. cytochrome c oxidase), that determine the positive biological responses such as increased metabolism, cellular regeneration and immunomodulation. The most clinically effective wavelength ranges are in the red (630-680 nm) and near infrared spectra (810-840 nm). Wavelength is one critical parameter of light among other factors such as dosage or energy density (J/cm2), treatment time and light delivery in pulses (cycles per second or Hz) in determining the efficiency of absorption, depth of penetration and ultimately the clinical outcomes. The effects of photobiomodulation are cumulative and can be clinically evident immediately after treatment or over a period of days.

Class III vs Class IV Lasers

Class 3B

5-500 mW Athermal Lower Energy and longer treatment duration optimizes healing and anti-inflammatory effects.

Class IV

>500 mW Thermal High energy and longer wavelengths result in tissue heating and less penetration.

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